Bioengineering Cartilage Growth, Maturation, and Form
نویسندگان
چکیده
منابع مشابه
Bioengineering of articular cartilage: past, present and future.
The treatment of cartilage defects poses a clinical challenge owing to the lack of intrinsic regenerative capacity of cartilage. The use of tissue engineering techniques to bioengineer articular cartilage is promising and may hold the key to the successful regeneration of cartilage tissue. Natural and synthetic biomaterials have been used to recreate the microarchitecture of articular cartilage...
متن کاملBioengineering Human Scaffold-free Cartilage Constructs Using Paediatric Auricular Tissue
Currently, patients with external ear deformities rely on hyaline cartilage grafts or silicone prosthesis to provide them with adequate external ear reconstruction. Scaffold-free auricular tissue engineering provides a means of creating patient specific cartilage constructs solely using their own cells, ensuring biocompatibility, long term stability, and reduced morbidity. Here, we have develop...
متن کاملA study of crystalline biomaterials for articular cartilage bioengineering
Article history: This study examines the su Received 22 November 2007 Accepted 16 March 2008 Available online 27 March 2008
متن کاملCCN1 Regulates Chondrocyte Maturation and Cartilage Development.
WNT/β-CATENIN signaling is involved in multiple aspects of skeletal development, including chondrocyte differentiation and maturation. Although the functions of β-CATENIN in chondrocytes have been extensively investigated through gain-of-function and loss-of-function mouse models, the precise downstream effectors through which β-CATENIN regulates these processes are not well defined. Here, we r...
متن کاملPTHrP regulates chondrocyte maturation in condylar cartilage.
PTHrP is a key factor regulating the pace of endochondral ossification during skeletal development. Mandibular advancement solicits a cascade of molecular responses in condylar cartilage. However, the pace of cellular maturation and its effects on condylar growth are still unknown. The purpose of this study was to evaluate the pattern of expression of PTHrP and correlate it to cellular dynamics...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 2008
ISSN: 0031-3998,1530-0447
DOI: 10.1203/pdr.0b013e31816b4fe5